Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181010 | 0.93 | DNMT3A (0.54) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10181758 | 0.91 | DNMT3A (0.53) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10181170 | 0.90 | DNMT3A (0.52) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10182210 | 0.89 | DNMT3A (0.54) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10180395 | 0.89 | CNR1 (0.50) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10181387 | 0.88 | DNMT3A (0.52) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL1154047 | 0.88 | ALDH1A1 (0.54) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10181435 | 0.88 | DNMT3A (0.48) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL10180958 | 0.88 | DNMT3A (0.49) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 | |
| SCHEMBL1153886 | 0.88 | PTPN11 (0.57) | DNMT3ANLRP3AKR1C3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215065-B1 | CCR10 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-11 | — | — | EP | claimed |