Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574910 | 0.93 | MEN1 (0.43) | RAB9AKCNH2HDAC3HDAC1HDAC2 | |
| SCHEMBL714677 | 0.93 | KCNH2 (0.43) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL5295527 | 0.93 | KCNH2 (0.43) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL1204768 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL45379 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL60682 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL619876 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL985190 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL7924615 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 | |
| SCHEMBL2849795 | 0.86 | NPC1 (0.53) | RAB9ANPC1JAK2PAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249845-B1 | Stabilized medium and high voltage cable insulation composition | BASF SE (DE) | 2012-07-11 | — | — | EP | claimed |
| EP-0323403-A2 | Lubricant composition | CIBA-GEIGY AG (CH) | 1989-07-05 | — | — | EP | disclosed |