Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 8/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5295527 | 1.00 | KCNH2 (0.43) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL10180717 | 0.93 | RAB9A (0.43) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL28574910 | 0.86 | MEN1 (0.43) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL8623193 | 0.84 | CNR2 (0.53) | — | |
| SCHEMBL8623189 | 0.83 | SHBG (0.44) | SMN1; SMN2 | |
| SCHEMBL17517232 | 0.82 | KIF11 (0.38) | KCNH2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL17517231 | 0.80 | DYRK1A (0.39) | MAPT | |
| SCHEMBL11342192 | 0.79 | MCHR1 (0.49) | KCNH2ALDH1A1DNM1TSHR | |
| SCHEMBL11331999 | 0.79 | MCHR1 (0.49) | KCNH2ALDH1A1DNM1TSHR | |
| SCHEMBL25557822 | 0.77 | MAPT (0.44) | KCNH2HDAC3HDAC1HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354529-B2 | Polyamine derivative and polyol derivative | BASF SE (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2511274-A2 | Polyamine derivative | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2484677-A1 | Polyamine derivative | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | MITA NARUYOSHI (JP) | 2012-03-01 | — | — | US | disclosed |
| US-8076478-B2 | Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance | BASF SE (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20110213077-A1 | Hydroquinone-containing polyesters having improved whiteness | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110204407-A1 | Power LED device with a reflector made of aromatic polyester and/or wholly aromatic polyester | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2342255-A1 | HYDROQUINONE-CONTAINING POLYESTERS HAVING IMPROVED WHITENESS | Solvay Advanced Polymers, L.L.C. (US) | 2011-07-13 | — | — | EP | disclosed |
| EP-2342766-A1 | POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER | Solvay Advanced Polymers, L.L.C. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010049531-A1 | POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010049526-A1 | HYDROQUINONE-CONTAINING POLYESTERS HAVING IMPROVED WHITENESS | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-05-06 | — | — | WO | disclosed |
| EP-1498442-B1 | Method for the preparation of a polyester block copolymer composition | DAICEL CHEM (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | CIBA CORPORATION | 2008-09-25 | — | — | US | disclosed |
| EP-1840127-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
| US-7196123-B2 | Polyester block copolymer composition and process for the preparation thereof | WATANABE JUN | 2007-03-27 | — | — | US | disclosed |
| EP-1498442-A2 | Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof | Daicel Chemical Industries, Ltd. (JP) | 2005-01-19 | — | — | EP | disclosed |
| US-20040010092-A1 | Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof | WATANABE JUN (JP) | 2004-01-15 | — | — | US | disclosed |
| US-6593434-B1 | Condensation polymerization, esterification, melt mixing or kneading; high molecular weight, low crystallinity | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1120432-A1 | PROCESS FOR THE PRODUCTION OF POLYESTER BLOCK COPOLYMERS, POLYESTER BLOCK COPOLYMER COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | H1-0, H1-3, NPM1 | KCNH2 335/4885HDAC3 1285/4885HDAC1 1190/4885 |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | H1-0, H1-3, H1-2 | KCNH2 141/4885HDAC3 2091/4885HDAC1 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.