Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44732 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL28622552 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL1204768 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL7924615 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL166835 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL2849795 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL60682 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL619876 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL45379 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL983245 | 1.00 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1657293-B1 | Diarylamine containing lubricating composition | AFTON CHEMICAL CORP (US) | 2017-10-11 | — | — | EP | claimed |
| US-8202829-B2 | Lubricating composition | AFTON CHEMICAL CORPORATION (US) | 2012-06-19 | — | — | US | claimed |
| EP-1657293-A2 | Diarylamine containing lubricating composition | Afton Chemical Corporation (US) | 2006-05-17 | — | — | EP | claimed |
| US-20060094607-A1 | Lubricating composition | AFTON CHEMICAL CORPORATION | 2006-05-04 | — | — | US | claimed |
| US-6599865-B1 | Lubricating oil, and a minor amount of an oil soluble alkylated diarylamine, an oil soluble alkylated phenothiazine, and an oil soluble sulfurized compound, said sulfurized compound selected from sulfurized olefins and fatty oils | ETHYL CORPORATION | 2003-07-29 | — | — | US | claimed |
| EP-4748909-A1 | LUBRICATING FLUID FOR INTERNAL COMBUSTION ENGINES FUELED WITH ALTERNATIVE COMBUSTION FUELS HAVING HIGH AUTO-IGNITION TEMPERATURES | Afton Chemical Corporation (US) | 2026-05-27 | — | — | EP | disclosed |
| US-12637632-B2 | Hydrolytically stable hydraulic lubricant | AFTON CHEMICAL CORPORATION (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630778-B2 | Detergent-free and low-ash lubricating composition | AFTON CHEMICAL CORPORATION (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260125612-A1 | LUBRICATING FLUID FOR AN ELECTRIC MOTOR | AFTON CHEMICAL CORP (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4737542-A1 | LUBRICATING FLUID FOR AN ELECTRIC MOTOR | Afton Chemical Corporation (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4737541-A1 | LUBRICATING FLUID FOR INTERNAL COMBUSTION ENGINES FUELED WITH ALTERNATIVE COMBUSTION FUELS HAVING HIGH AUTO-IGNITION TEMPERATURES | Afton Chemical Corporation (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260117141-A1 | HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT | AFTON CHEMICAL CORP (US) | 2026-04-30 | — | — | US | disclosed |
| EP-1369469-A1 | An antioxidant additives combination for lubricants containing a molybdenum complex and an alkylated phenothiazine | ETHYL CORPORATION (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20030224950-A1 | Antioxidant combination for oxidation and deposit control in lubricants containing molybdenum and alkylated phenothiazine | AFTON CHEMICAL CORPORATION | 2003-12-04 | — | — | US | disclosed |
| US-6599865-B1 | Lubricating oil, and a minor amount of an oil soluble alkylated diarylamine, an oil soluble alkylated phenothiazine, and an oil soluble sulfurized compound, said sulfurized compound selected from sulfurized olefins and fatty oils | ETHYL CORPORATION | 2003-07-29 | — | — | US | disclosed |
| US-6184262-B1 | Benzotriazole stabilizers for polyols and polyurethane foam | R. T. VANDERBILT COMPANY, INC. | 2001-02-06 | — | — | US | disclosed |
| EP-0839861-A2 | Benzotriazole stabilizers for polyols and polyurethane foam | R.T. VANDERBILT COMPANY, Inc. (US) | 1998-05-06 | — | — | EP | disclosed |
| US-4292196-A | Catalyst recovery | UOP INC. (US) | 1981-09-29 | — | — | US | disclosed |
| US-4250115-A | Preparation of tertiary amines | UOP INC. (US) | 1981-02-10 | — | — | US | disclosed |
| US-4207260-A | Preparation of tertiary amines | UOP INC. (US) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125612-A1 | LUBRICATING FLUID FOR AN ELECTRIC MOTOR | TST, AS3MT, SLC6A6 | NPC1 4573/4885JAK2 522/4885RAB9A 4267/4885 |
| US-12637632-B2 | Hydrolytically stable hydraulic lubricant | TST, TASP1, GSTP1 | NPC1 4194/4885JAK2 2575/4885RAB9A 4751/4885 |
| US-12630778-B2 | Detergent-free and low-ash lubricating composition | SFN, PSPH, C9 | NPC1 3720/4885JAK2 3996/4885RAB9A 2413/4885 |
| US-20260117141-A1 | HYDROLYTICALLY STABLE HYDRAULIC LUBRICANT | TST, TASP1, GSTP1 | NPC1 4194/4885JAK2 2575/4885RAB9A 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.