SCHEMBL10180848

SCHEMBL10180848

CCC1=CC(=O)C(CO)O1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.32
MAPT P10636 1/20 0.32
ACP1 P24666 1/20 0.32
CDC25B P30305 1/20 0.32
RECQL P46063 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTPN2 P17706 1/20 0.32
DUSP3 P51452 1/20 0.32
HPSE Q9Y251 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468146 0.71
SCHEMBL27782085 0.64
SCHEMBL736870 0.63
SCHEMBL9818508 0.63 SLC2A1 (0.33)
SCHEMBL16359857 0.61 LMNA (0.41) PTPN1MAPTACP1CDC25BRECQL
SCHEMBL11474613 0.61
SCHEMBL10618058 0.58 SMN1; SMN2 (0.44) MAPT
SCHEMBL593299 0.58 SMN1; SMN2 (0.44) MAPT
SCHEMBL5973734 0.58
SCHEMBL3501010 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2353403-B1 Use of 1-(2,4-dihydroxy-phenyl)-3-(3-hydroxy-4-methoxy-phenyl)-propan-1-on SYMRISE AG (DE) 2012-07-11 EP claimed