Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL220276 | 0.97 | — | — | |
| Iodide SCHEMBL2988326 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL6005004 | 0.80 | KDM4E (0.34) | — | |
| Dipyridyl SCHEMBL3711450 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL29351528 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL5922 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL29907716 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL497901 | 0.65 | KDM4E (0.93) | — | |
| Dipyridyl SCHEMBL10395611 | 0.65 | KDM4E (0.93) | — | |
| Dipyridyl SCHEMBL1535115 | 0.65 | KDM4E (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215035-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2025-07-03 | — | — | US | disclosed |
| EP-4188930-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | BAYER AG (DE) | 2024-10-23 | — | — | EP | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-11871653-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-01-09 | — | — | US | disclosed |
| US-20230391769-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND THERAPEUTIC USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-07 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20210070707-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| CN-111606956-A | Organic electroluminescent material and device | 环球展览公司 | 2020-09-01 | — | — | CN | disclosed |
| US-20200274079-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-08-27 | — | — | US | disclosed |
| US-20200190030-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2020-06-18 | — | — | US | disclosed |
| US-20030004339-A1 | Process for the production of quinazolines | PFIZER INC. | 2003-01-02 | — | — | US | disclosed |
| WO-2002094815-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LIMITED (GB) | 2002-11-28 | — | — | WO | disclosed |
| CN-1073110-C | Process for the preparation of biphenyl derivatives | AMERICAN HOME PROD (US) | 2001-10-17 | — | — | CN | disclosed |
| US-5977372-A | Chloro or bromo[2-[2-(tert-butyl)-2H-tetrazol-5-yl]phenyl]zinc intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| CN-1192214-A | Process for the preparation of biphenyl derivatives | AMERICAN HOME PROD (US) | 1998-09-02 | — | — | CN | disclosed |
| EP-0846117-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5760220-A | REACTING PROTECTED TETRAZOLYLPHENYL ZINC HALIDE WITH HALOPHENYLMETHYL PYRIDO/2,3-D/PYRIMIDONE IN PRESENCE OF PALLADIUM OR NICKEL CATALYST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1996040684-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4710507-A | Quinolone inotropic agents | PFIZER INC. (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0148623-A2 | Quinolone inotropic agents | Pfizer Limited (GB) | 1985-07-17 | — | — | EP | disclosed |