SCHEMBL10182040

SCHEMBL10182040

C[C@@H]([C]=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 4/20 0.47
DPP9 Q86TI2 4/20 0.47
DPP7 Q9UHL4 4/20 0.47
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
NMT2 O60551 1/20 0.43
NMT1 P30419 1/20 0.43
DPP4 P27487 1/20 0.42
GSR P00390 1/20 0.41
SIRT6 Q8N6T7 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
MMP2 P08253 1/20 0.39
CPB2 Q96IY4 2/20 0.38
NPY4R P50391 2/20 0.36
FURIN P09958 1/20 0.36
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
NPY5R Q15761 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671395 0.93 DPP8 (0.52) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL9117592 0.93 DPP8 (0.52) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL9117596 0.93 DPP8 (0.52) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL28081216 0.92 NMT1 (0.46) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL5891973 0.91 DPP8 (0.47) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL9818089 0.90 NMT2 (0.43) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL16468935 0.88 DPP8 (0.49) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL10703971 0.88 DPP7 (0.51) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL2197281 0.84 DPP8 (0.46) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL9638006 0.84 DPP7 (0.46) DPP8DPP9DPP7GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385933-B1 CULTURE MEDIUM FOR CELL GROWTH AND TRANSFECTION LIFE TECHNOLOGIES CORP (US) 2012-07-11 EP claimed