Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182040 | 0.91 | DPP8 (0.47) | DPP8DPP9DPP4NMT2NMT1 | |
| SCHEMBL2196149 | 0.90 | DPP4 (0.54) | DPP8DPP9DPP4FOLH1CYP2D6 | |
| SCHEMBL1649812 | 0.86 | FOLH1 (0.48) | DPP8DPP9DPP4FOLH1NMT2 | |
| SCHEMBL10943106 | 0.85 | DPP4 (0.61) | DPP8DPP9DPP4FOLH1CYP2D6 | |
| SCHEMBL27262388 | 0.85 | DPP4 (0.61) | DPP8DPP9DPP4FOLH1CYP2D6 | |
| SCHEMBL31735179 | 0.85 | FOLH1 (0.52) | DPP8DPP9DPP4FOLH1NMT2 | |
| SCHEMBL18950261 | 0.84 | FOLH1 (0.51) | DPP8DPP9DPP4FOLH1NMT2 | |
| SCHEMBL9818089 | 0.84 | NMT2 (0.43) | DPP8DPP9FOLH1NMT2NMT1 | |
| SCHEMBL30394354 | 0.84 | FOLH1 (0.66) | DPP8DPP9DPP4FOLH1CPB2 | |
| SCHEMBL9117592 | 0.84 | DPP8 (0.52) | DPP8DPP9DPP4DPP7GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125698-B2 | Polynucleotides, materials incorporating them, and methods for using them | VIALACTIA BIOSCIENCE (NZ) LIMITED (NZ) | 2006-10-24 | — | — | US | disclosed |