Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 12/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410583 | 0.87 | MKNK1 (0.40) | MKNK1GRM5GRM4MKNK2 | |
| SCHEMBL10182240 | 0.84 | GRM4 (0.36) | MKNK1GRM5GRM2GRM4MKNK2 | |
| SCHEMBL12410434 | 0.77 | GRM5 (0.44) | MKNK1GRM5GRM4MKNK2 | |
| SCHEMBL10233625 | 0.76 | IRAK4 (0.46) | GRM2IRAK4TYK2 | |
| SCHEMBL3394370 | 0.76 | MKNK1 (0.35) | MKNK1GRM5GRM2GRM4MKNK2 | |
| SCHEMBL12410578 | 0.76 | GABRA1 (0.39) | MKNK1GRM5IRAK4 | |
| SCHEMBL21791746 | 0.72 | PIM1 (0.36) | GRM2IRAK4 | |
| SCHEMBL12410500 | 0.71 | MKNK1 (0.35) | MKNK1GRM5GRM4MKNK2IRAK4 | |
| SCHEMBL10182229 | 0.70 | IRAK4 (0.43) | IRAK4MELK | |
| SCHEMBL10182009 | 0.69 | IRAK4 (0.42) | MKNK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165345-A1 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | MKNK1 1426/4885GRM5 1306/4885GRM2 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.