SCHEMBL10182633

SCHEMBL10182633

CCCCOC1C(OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)OC(COC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.56
PTPN2 P17706 1/20 0.50
PTPN11 Q06124 1/20 0.50
USP2 O75604 2/20 0.48
F11 P03951 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TMPRSS2 O15393 1/20 0.48
PDE5A O76074 1/20 0.48
HMGCR P04035 1/20 0.48
CYP1A2 P05177 1/20 0.48
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
HSPD1 P10809 1/20 0.48
CYP2C9 P11712 1/20 0.48
CA6 P23280 1/20 0.48
TBXAS1 P24557 1/20 0.48
MAPK3 P27361 1/20 0.48
MAPK1 P28482 1/20 0.48
HSPE1 P61604 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15483270 1.00 PTPN1 (0.56) PTPN1PTPN2PTPN11USP2F11
SCHEMBL14817669 1.00 PTPN1 (0.56) PTPN1PTPN2PTPN11USP2F11
SCHEMBL14413572 0.94 PTPN1 (0.51) PTPN1PTPN2PTPN11USP2F11
SCHEMBL11985212 0.94 PTPN1 (0.48) PTPN1PTPN2PTPN11USP2F11
SCHEMBL17850338 0.90 PTPN1 (0.49) PTPN1PTPN2PTPN11USP2F11
SCHEMBL26822757 0.90 PTPN1 (0.49) PTPN1PTPN2PTPN11USP2F11
SCHEMBL15833434 0.89 PTPN1 (0.48) PTPN1PTPN2PTPN11USP2F11
SCHEMBL16299427 0.89 PTPN1 (0.48) PTPN1PTPN2PTPN11USP2F11
SCHEMBL16383651 0.89 MEN1 (0.47) PTPN1PTPN2PTPN11USP2CA1
SCHEMBL4875707 0.88 PTPN1 (0.68) PTPN1PTPN2PTPN11USP2F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120208993-A1 SYNTHETIC HEPARIN TRISACCHARIDES ALCHEMIA LIMITED (AU) 2012-08-16 US disclosed
US-8114970-B2 Synthetic heparin monosaccharides ALCHEMIA LIMITED (AU) 2012-02-14 US disclosed
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA LIMITED (AU) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES HPSE, DDOST, STT3A PTPN1 695/4885PTPN2 601/4885PTPN11 261/4885
US-20120208993-A1 SYNTHETIC HEPARIN TRISACCHARIDES HPSE, SERPINC1, DDOST PTPN1 856/4885PTPN2 968/4885PTPN11 529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.