Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 4/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10233571 | 0.90 | RIPK2 (0.42) | IRAK4NTRK1FLT3CLK2LRRK2 | |
| SCHEMBL15747006 | 0.89 | IRAK4 (0.40) | IRAK4CLK2LRRK2ABL1KAT6A | |
| SCHEMBL10182229 | 0.89 | IRAK4 (0.43) | IRAK4CLK2LRRK2ABL1KAT6A | |
| SCHEMBL10182013 | 0.88 | NTRK1 (0.40) | IRAK4NTRK1FLT3CLK2LRRK2 | |
| SCHEMBL10182009 | 0.87 | IRAK4 (0.42) | IRAK4CLK2LRRK2ABL1KAT6A | |
| SCHEMBL10233599 | 0.84 | PTGS2 (0.54) | IRAK4KAT6APTGS1PTGS2 | |
| SCHEMBL10233520 | 0.83 | CLK2 (0.41) | IRAK4CLK2LRRK2ABL1 | |
| SCHEMBL10231655 | 0.81 | P4HTM (0.41) | IRAK4CLK2LRRK2ABL1KAT6A | |
| SCHEMBL10233376 | 0.80 | RIPK2 (0.40) | IRAK4CLK2LRRK2ABL1MKNK1 | |
| SCHEMBL10233351 | 0.78 | RIPK2 (0.43) | IRAK4CLK2LRRK2ABL1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | IRAK4 4536/4885NTRK1 3944/4885FLT3 4147/4885 |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | IRAK4 4536/4885NTRK1 3944/4885FLT3 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.