SCHEMBL1018485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018751	0.87	HRH3 (0.52)	HRH3L3MBTL1ALDH1A1NPSR1KMT2A
	SCHEMBL1018354	0.83	CA9 (0.48)	HRH3L3MBTL1ALDH1A1NPSR1KMT2A
	SCHEMBL1018390	0.83	HRH3 (0.47)	HRH3L3MBTL1ALDH1A1NPSR1KMT2A
	SCHEMBL1018680	0.83	ABHD6 (0.48)	HRH3ALDH1A1NPSR1KMT2AATM
	SCHEMBL1020441	0.82	ALDH1A1 (0.50)	HRH3L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1604050	0.82	ALDH1A1 (0.50)	HRH3L3MBTL1ALDH1A1KMT2AKDM4E
	SCHEMBL1014239	0.81	ABCB1 (0.45)	HRH3L3MBTL1ALDH1A1KDM4EMAPT
	SCHEMBL1017409	0.81	KMT2A (0.59)	L3MBTL1ALDH1A1NPSR1KMT2APOLB
	SCHEMBL1017926	0.81	KDM4E (0.56)	L3MBTL1ALDH1A1NPSR1KMT2APOLB
	SCHEMBL1016559	0.80	ABCB1 (0.45)	HRH3L3MBTL1ALDH1A1NPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.