Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186527 | 1.00 | DGAT1 (0.57) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10185532 | 0.93 | DGAT1 (0.57) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL662997 | 0.93 | DGAT1 (0.57) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL662996 | 0.93 | DGAT1 (0.57) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10185798 | 0.89 | DGAT1 (0.52) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13117565 | 0.86 | DGAT1 (0.53) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL661474 | 0.84 | DGAT1 (0.52) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL661473 | 0.84 | DGAT1 (0.52) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10185140 | 0.84 | DGAT1 (0.52) | DGAT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL662487 | 0.84 | DGAT1 (0.56) | DGAT1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | DGAT1 1/4885HDAC3 974/4885HDAC4 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.