SCHEMBL1018545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018553	0.87	HTT (0.47)	HTTGAAHSP90AA1KDM4EPOLB
	SCHEMBL382174	0.86	GAA (0.50)	HTTGAAKDM4EPOLBRECQL
	SCHEMBL1021339	0.85	KDM4E (0.49)	HTTHSP90AA1KDM4EPOLBRECQL
	SCHEMBL1018849	0.84	HSP90AA1 (0.56)	GAAHSP90AA1KDM4EPOLBCA12
	SCHEMBL1018764	0.83	HSP90AA1 (0.44)	GAAHSP90AA1CA12CA1CA2
	SCHEMBL18318870	0.82	GAA (0.58)	HTTGAAKDM4EPOLBLMNA
	SCHEMBL23159299	0.80	HSP90AA1 (0.46)	GAAHSP90AA1KDM4EPOLBCA12
	SCHEMBL15614388	0.80	KDM4E (0.45)	HTTGAAKDM4EPOLBRECQL
	SCHEMBL1020114	0.80	HSP90AA1 (0.42)	GAAHSP90AA1KDM4ETSHRMAPT
	SCHEMBL20379942	0.80	HTT (0.48)	HTTGAAHSP90AA1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.