SCHEMBL1018764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1022138	0.89	HSP90AA1 (0.42)	HSP90AA1KDRCHEK1AURKADAPK3
	SCHEMBL1018574	0.88	CHEK1 (0.41)	HSP90AA1KDRCHEK1AURKADAPK3
	SCHEMBL1019195	0.87	HSP90AA1 (0.40)	HSP90AA1BACE1MAPTEGFRTSHR
	SCHEMBL1018545	0.83	HTT (0.48)	HSP90AA1ABL1GAAMAPTCA12
	SCHEMBL1020114	0.82	HSP90AA1 (0.42)	HSP90AA1TDP1GAAMAPTTSHR
	SCHEMBL12726581	0.81	TDP1 (0.38)	KDRCHEK1AURKADAPK3JAK2
	SCHEMBL12766090	0.81	THRA (0.38)	HSP90AA1KDRCHEK1AURKADAPK3
	SCHEMBL1019663	0.79	FLT3 (0.40)	KDRCHEK1AURKADAPK3JAK2
	SCHEMBL1019840	0.78	EGFR (0.39)	HSP90AA1BACE1MAPTEGFRLMNA
	SCHEMBL1018849	0.78	HSP90AA1 (0.56)	HSP90AA1TDP1GAACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.