Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186457 | 0.95 | CCR3 (0.46) | CCR3SCN9ADGAT1HRH1ACSL1 | |
| SCHEMBL10185105 | 0.94 | CCR3 (0.49) | CCR3PTGDR2HRH1ACSL1HPGD | |
| SCHEMBL10186159 | 0.93 | HRH3 (0.43) | CCR3SCN9ADGAT1HRH1ACSL1 | |
| SCHEMBL10185364 | 0.92 | CCR3 (0.44) | CCR3PTGDR2HRH1ACSL1HPGD | |
| SCHEMBL10185451 | 0.92 | DGAT1 (0.46) | CCR3DGAT1HPGDHRH3 | |
| SCHEMBL662784 | 0.92 | DGAT1 (0.46) | CCR3DGAT1HPGDHRH3 | |
| SCHEMBL662783 | 0.92 | DGAT1 (0.46) | CCR3DGAT1HPGDHRH3 | |
| SCHEMBL10186165 | 0.92 | CCR3 (0.43) | CCR3SCN9APTGDR2DGAT1HRH1 | |
| SCHEMBL10185788 | 0.91 | CCR3 (0.45) | CCR3SCN9ADGAT1HRH1ACSL1 | |
| SCHEMBL10186081 | 0.90 | CCR3 (0.43) | CCR3SCN9AHRH1HPGDP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | CCR3 4296/4885SCN9A 3832/4885PTGDR2 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.