Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791271 | 0.88 | NPC1 (0.37) | NPC1STING1TNK2ALDH1A1BACE1 | |
| SCHEMBL24917291 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HTTPOLB | |
| SCHEMBL10149693 | 0.82 | MEN1 (0.38) | NPC1ALDH1A1POLB | |
| SCHEMBL882554 | 0.82 | MEN1 (0.38) | NPC1ALDH1A1POLB | |
| SCHEMBL24791257 | 0.81 | NPC1 (0.40) | NPC1STING1BACE1CHRNB2CHRNA5 | |
| SCHEMBL20059148 | 0.79 | NPC1 (0.38) | NPC1TNK2ALDH1A1BACE1CHRNB2 | |
| SCHEMBL10187408 | 0.79 | NPC1 (0.38) | NPC1TNK2ALDH1A1BACE1CHRNB2 | |
| SCHEMBL881488 | 0.74 | MEN1 (0.47) | ALDH1A1POLB | |
| SCHEMBL24791256 | 0.73 | NPC1 (0.39) | NPC1TNK2ALDH1A1BACE1CHRNB2 | |
| SCHEMBL10187389 | 0.72 | NPC1 (0.39) | NPC1TNK2ALDH1A1BACE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039791-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |