Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791271 | 0.91 | NPC1 (0.37) | NPC1TNK2DOT1LALDH1A1RIPK1 | |
| SCHEMBL24606380 | 0.82 | NPC1 (0.38) | NPC1DOT1LRIPK1CHRNB2CHRNA5 | |
| SCHEMBL16480684 | 0.79 | ALDH1A1 (0.38) | DOT1LALDH1A1RIPK1POLRMTPOLB | |
| SCHEMBL10187245 | 0.79 | NPC1 (0.36) | NPC1TNK2ALDH1A1BACE1CHRNB2 | |
| SCHEMBL881460 | 0.79 | ALDH1A1 (0.38) | DOT1LALDH1A1RIPK1POLRMTPOLB | |
| SCHEMBL10187389 | 0.78 | NPC1 (0.39) | NPC1TNK2ALDH1A1RIPK1BACE1 | |
| SCHEMBL26229753 | 0.77 | POLRMT (0.47) | TNK2DOT1LRIPK1POLRMT | |
| SCHEMBL17129844 | 0.77 | ALDH1A1 (0.36) | TNK2DOT1LALDH1A1RIPK1POLRMT | |
| SCHEMBL16480685 | 0.76 | MEN1 (0.46) | DOT1LALDH1A1RIPK1POLRMTPOLB | |
| SCHEMBL882318 | 0.76 | MEN1 (0.46) | DOT1LALDH1A1RIPK1POLRMTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |