SCHEMBL1018727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019930	0.98	ALDH1A1 (0.46)	MTNR1BPRMT5WDR77ALDH1A1TSHR
	SCHEMBL1018461	0.97	ALDH1A1 (0.47)	MTNR1BPRMT5WDR77ALDH1A1TSHR
	SCHEMBL1018858	0.92	MTNR1B (0.45)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1014301	0.90	ALDH1A1 (0.46)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1016505	0.90	ALDH1A1 (0.48)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1017450	0.90	MTNR1B (0.44)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1018244	0.89	ALDH1A1 (0.50)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1014599	0.89	ALDH1A1 (0.50)	MTNR1BALDH1A1TSHRKMT2AACHE
	SCHEMBL1017588	0.89	MTNR1B (0.52)	MTNR1BALDH1A1TSHRKMT2ACBX7
	SCHEMBL1018313	0.89	MTNR1B (0.46)	MTNR1BALDH1A1TSHRKMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.