Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21582525 | 0.89 | MAPT (0.39) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL30271360 | 0.83 | ALDH1A1 (0.35) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL12113205 | 0.83 | PIK3CD (0.35) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL2955940 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL23458719 | 0.80 | HSD17B10 (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL12113611 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL29982955 | 0.80 | HSD17B10 (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL26329035 | 0.79 | CYP1A2 (0.49) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL11803401 | 0.78 | KDM4E (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL12520557 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |