Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348569 | 0.90 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 | |
| SCHEMBL26329102 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19TLR8BCHE | |
| SCHEMBL11744829 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 | |
| SCHEMBL16931148 | 0.82 | TSHR (0.44) | TLR8ALDH1A1TSHR | |
| SCHEMBL10187308 | 0.79 | ALDH1A1 (0.41) | TLR8NPC1RAB9AMEN1MAPT | |
| SCHEMBL15740111 | 0.79 | CA12 (0.37) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 | |
| SCHEMBL26329033 | 0.79 | LTA4H (0.41) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 | |
| SCHEMBL11748538 | 0.77 | TLR8 (0.50) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 | |
| SCHEMBL28413262 | 0.76 | BCHE (0.47) | CYP1A2CYP2C9CYP2C19TLR8BCHE | |
| SCHEMBL19605731 | 0.75 | MEN1 (0.36) | CYP1A2CYP2C9CYP2C19MCHR1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | CYP1A2 4609/4885CYP2C9 4807/4885CYP2C19 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.