Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | IKBKB | O14920 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813041 | 0.84 | SYK (0.71) | SCN9AKCNH2SCN5AKMT2ANPC1 | |
| SCHEMBL14618917 | 0.82 | MEN1 (0.71) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL23780649 | 0.81 | SCN9A (0.72) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL12813301 | 0.81 | EGFR (0.71) | SCN9ASCN5ANPC1RAB9ACDK5 | |
| SCHEMBL3979028 | 0.81 | MEN1 (0.69) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL3972344 | 0.81 | MEN1 (0.74) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL12813201 | 0.80 | SCN9A (0.66) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL3454504 | 0.80 | SCN9A (0.55) | SCN9AKCNH2SCN5AMEN1KMT2A | |
| SCHEMBL1121223 | 0.79 | RAB9A (0.67) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4467991 | 0.79 | ROCK1 (0.63) | SCN9AKCNH2SCN5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |