Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513695 | 1.00 | KDM4E (0.47) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL24196192 | 0.84 | KDM4E (0.69) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL7476342 | 0.84 | ROCK2 (0.46) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL1776789 | 0.81 | PTPN11 (0.49) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL15416295 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL20089101 | 0.79 | PTPN11 (0.48) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL2255793 | 0.78 | POLB (0.47) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL5805886 | 0.78 | ALDH1A1 (0.55) | KDM4EPTPN11ALDH1A1TSHRGAA | |
| SCHEMBL25695026 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL22638875 | 0.75 | PTPN11 (0.36) | KDM4EPTPN11ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206728-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | COILED THERAPEUTICS, INC. | 2025-06-26 | — | — | US | disclosed |
| WO-2025072722-A1 | METHODS FOR TREATING CANCERS ASSOCIATED WITH TRANSFORMING ACIDIC COILED-COIL PROTEINS | A2A PHARMACEUTICALS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| EP-4499625-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A Pharmaceuticals, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| US-11986475-B1 | Compositions and methods for treating cancer | A2A PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20240156813-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | COILED THERAPEUTICS, INC. | 2024-05-16 | — | — | US | disclosed |
| WO-2023183520-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023183520-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | A2A PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206728-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | NTPCR, PTPRC, NFATC1 | KDM4E 4462/4885PTPN11 248/4885ALDH1A1 1208/4885 |
| US-11986475-B1 | Compositions and methods for treating cancer | NTPCR, PTPRC, NFATC1 | KDM4E 4462/4885PTPN11 248/4885ALDH1A1 1208/4885 |
| US-20240156813-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | NTPCR, PTPRC, NFATC1 | KDM4E 4462/4885PTPN11 248/4885ALDH1A1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.