Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.59 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.57 |
| ▸ | USP5 | P45974 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RGS12 | O14924 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882594 | 0.90 | USP9X (0.67) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL10124840 | 0.82 | USP9X (0.72) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL13349344 | 0.81 | USP9X (0.78) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL17986432 | 0.75 | USP9X (1.00) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL864117 | 0.75 | USP9X (0.78) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL23171294 | 0.75 | USP9X (1.00) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL864115 | 0.75 | USP9X (0.78) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL16647256 | 0.75 | USP9X (1.00) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL17986431 | 0.75 | USP9X (1.00) | USP9XUCHL1USP5STAT3USP24 | |
| SCHEMBL864116 | 0.75 | USP9X (0.78) | USP9XUCHL1USP5STAT3USP24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040527-A2 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | WO | disclosed |