SCHEMBL1018798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1014648	0.88	ALDH1A1 (0.39)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1014267	0.85	HRH3 (0.39)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1018373	0.83	TMEM97 (0.40)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1014022	0.82	HRH3 (0.48)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1014992	0.82	TMEM97 (0.42)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1018277	0.80	TMEM97 (0.40)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1017670	0.79	TMEM97 (0.41)	HRH3TMEM97SIGMAR1HTR1AHRH2
	SCHEMBL1015259	0.79	WNT1 (0.47)	HRH3
	SCHEMBL1016821	0.78	ALDH1A1 (0.45)	HRH3TMEM97SIGMAR1CHRM4ALDH1A1
	SCHEMBL1017675	0.78	MAPK8 (0.41)	HRH3TMEM97SIGMAR1HTR1AHRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.