SCHEMBL1018845

SCHEMBL1018845

FC(F)(Br)C(F)(Cl)CCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098793 0.81
SCHEMBL2490733 0.74
SCHEMBL1018924 0.74
SCHEMBL8348097 0.74
SCHEMBL27789774 0.74
SCHEMBL1019951 0.70
SCHEMBL248018 0.69
SCHEMBL6330818 0.69 CYP3A4 (0.32)
SCHEMBL370548 0.67
SCHEMBL9719531 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634397-B2 Process and intermediates for the preparation of Fluensulfone ADAMA MAKHTESHIM LTD. (IL) 2023-04-25 US claimed
US-20220002258-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE ADAMA MAKHTESHIM LTD. (IL) 2022-01-06 US claimed
CN-112707790-A Synthesis method of 2-chloro-1,4-dibromo-1,1,2-trifluorobutane 南开大学 2021-04-27 CN claimed
US-11634397-B2 Process and intermediates for the preparation of Fluensulfone ADAMA MAKHTESHIM LTD. (IL) 2023-04-25 US disclosed
CN-114805240-B Method for synthesizing fluoro-olefine sulfone by one-pot method 湖南速博生物技术有限公司 2022-09-16 CN disclosed
CN-114805010-A Preparation method of 4-halogenated-1, 1, 2-trifluoro-1-butene 河北桑迪亚医药技术有限责任公司 2022-07-29 CN disclosed
CN-114805240-A Method for synthesizing fluoro-olefine sulfone by one-pot method 湖南速博生物技术有限公司 2022-07-29 CN disclosed
US-20220002258-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE ADAMA MAKHTESHIM LTD. (IL) 2022-01-06 US disclosed
CN-112930342-A Process and intermediates for preparing difluoride sulfones 阿达玛马克西姆有限公司 2021-06-08 CN disclosed
CN-112707790-A Synthesis method of 2-chloro-1,4-dibromo-1,1,2-trifluorobutane 南开大学 2021-04-27 CN disclosed
CN-112707790-A Synthesis method of 2-chloro-1,4-dibromo-1,1,2-trifluorobutane 南开大学 2021-04-27 CN disclosed
EP-1506147-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETYLENES Bayer CropScience AG (DE) 2005-02-16 EP disclosed
EP-1506150-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES Bayer CropScience Aktiengesellschaft (DE) 2005-02-16 EP disclosed
WO-2003095395-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETYLENES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-11-20 WO disclosed
WO-2003095401-A1 METHOD FOR THE PRODUCTION OF SUBSTITUTED TRIFLUOROETHYLENES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-11-20 WO disclosed
US-20030181615-A1 Bromosulphonated fluorinated cross-linkabke elastomers based on vinylidene fluoride having low t9 and processes for their preparation HYDRO-QUEBEC (CA) 2003-09-25 US disclosed
EP-1289915-A2 BROMOSULPHONATED FLUORINATED CROSSLINKABLE ELASTOMERS BASED ON VINYLIDENE FLUORIDE HAVING VERY LOW TG AND METHOD FOR PREPARING SAME HYDRO-QUEBEC (CA) 2003-03-12 EP disclosed
WO-2001096268-A2 BROMOSULPHONATED FLUORINATED CROSSLINKABLE ELASTOMERS BASED ON VINYLIDENE FLUORIDE HAVING VERY LOW TG AND METHOD FOR PREPARING SAME HYDRO-QUéBEC (CA) 2001-12-20 WO disclosed
US-6281312-B1 USING AN ORGANOHALOGEN COMPOUND NIPPON MEKTRON, LTD. (JP) 2001-08-28 US disclosed
US-6160053-A Flourine-containing copolymer composition NIPPON MEDTRON, LIMITED (JP) 2000-12-12 US disclosed