SCHEMBL101891

SCHEMBL101891

Nc1c(O)cccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL845067 0.95 G6PD (0.43)
Hydrochloric Acid SCHEMBL845068 0.95 G6PD (0.43)
SCHEMBL113475 0.80
SCHEMBL69654 0.80
Methane SCHEMBL1703075 0.77 SMN1; SMN2 (0.43)
Bromide SCHEMBL29216576 0.77 CES2 (0.39)
Iodide SCHEMBL29216564 0.77 CES2 (0.39)
Hydrochloric Acid SCHEMBL7423355 0.77 CES2 (0.39)
Hydrochloric Acid SCHEMBL766671 0.77 G6PD (0.54)
Phenol SCHEMBL27889282 0.75 CA14 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113441135-B Preparation method of 2-amino-3H-phenoxazin-3-one or derivative thereof 兰州大学 2022-09-20 CN claimed
CN-113441135-A Preparation method of 2-amino-3H-phenoxazin-3-one or derivative thereof 兰州大学 2021-09-28 CN claimed
EP-0624567-A2 Derivatives of 3-fluorophenol, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP claimed
JP-7070007-A None JP disclosed
EP-4709425-A1 LINKER COMPOUNDS AND LIGAND-DRUG CONJUGATES, PREPARATION METHODS AND USES THEREOF Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (CN) 2026-03-18 EP disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
CN-119241427-A Method for comprehensively and efficiently synthesizing anticancer drug regorafenib 董帅圻 2025-01-03 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
WO-2024235105-A1 LINKER COMPOUNDS AND LIGAND-DRUG CONJUGATES, PREPARATION METHODS AND USES THEREOF BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD. (CN) 2024-11-21 WO disclosed
US-5780483-A IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION (US) 1998-07-14 US disclosed
EP-0809492-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-12-03 EP disclosed
WO-1997029743-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-08-21 WO disclosed
WO-1996025157-A1 IL-8 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-22 WO disclosed
US-5410082-A Process for preparing amines CLARIANT GMBH (DE) 1995-04-25 US disclosed
JP-H0770007-A NOVEL DERIVATIVE OF 3-FLUOROPHENOL, ITS PRODUCTION AND USE HOECHST AG 1995-03-14 JP disclosed
EP-0628536-A2 Process for the preparation of amines HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-14 EP disclosed
EP-0624567-A2 Derivatives of 3-fluorophenol, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-17 EP disclosed
EP-0462800-A2 Inhibitors of HIV reverse transcriptase MERCK & CO. INC. (US) 1991-12-27 EP disclosed