Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569920 | 0.87 | POLB (0.61) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL13572927 | 0.87 | ATM (0.59) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL6407665 | 0.87 | ATM (0.59) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL14999596 | 0.87 | ATM (0.59) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL28741666 | 0.85 | SYK (0.54) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL19772848 | 0.84 | ATM (0.54) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL28370653 | 0.84 | CTSL (0.62) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL18857044 | 0.84 | SMN1; SMN2 (0.62) | ATMCTSLMEN1KMT2ACYP3A4 | |
| SCHEMBL15414625 | 0.84 | ATM (0.57) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL938011 | 0.84 | ATM (0.57) | ATMCTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013122888-A2 | METHODS OF TREATING BACTERIAL INFECTIONS | REMPEX PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | WO | disclosed |
| WO-2012021455-A1 | CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |