Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 5/20 | 0.59 |
| ▸ | CTSS | P25774 | 5/20 | 0.59 |
| ▸ | CTSL | P07711 | 4/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999596 | 1.00 | ATM (0.59) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL13572927 | 1.00 | ATM (0.59) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL19569920 | 0.88 | POLB (0.61) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL4033719 | 0.87 | NPC1 (0.65) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL13534727 | 0.87 | NPC1 (0.65) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL398460 | 0.87 | ATM (0.59) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL5268187 | 0.87 | ATM (0.59) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL1547277 | 0.87 | ATM (0.59) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL10189480 | 0.87 | ATM (0.53) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL5194569 | 0.86 | ATM (0.58) | ATMCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196556-A1 | CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-111741951-B | Amide compound or salt thereof, agricultural/horticultural fungicide containing the same, and method for using the same | 日本农药株式会社 | 2023-08-18 | — | — | CN | disclosed |
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | VIFOR (INTERNATIONAL) LTD. (CH) | 2018-05-17 | — | — | US | disclosed |
| WO-2017190107-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-11-02 | — | — | WO | disclosed |
| WO-2009153721-A1 | NICOTINAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |
| CN-1309715-C | N-acylaminoacetonitrile derivatives and their use for controlling parasites | NOVARTIS AG (CH) | 2007-04-11 | — | — | CN | disclosed |
| CN-1649579-A | N-acylaminoacetonitrile derivatives and their use for controlling parasites | NOVARTIS AG (CH) | 2005-08-03 | — | — | CN | disclosed |
| US-20050042245-A1 | Oil-in-water emulsion formulation of insecticides | TARANTA CLAUDE (DE) | 2005-02-24 | — | — | US | disclosed |
| CN-1545500-A | Carbonyloxy-cyanomethyl compounds as antiparasitic agents | 诺瓦提斯公司 | 2004-11-10 | — | — | CN | disclosed |
| CN-1193321-A | Microbiocidal benzotriazoles compounds | BAYER AG (DE) | 1998-09-16 | — | — | CN | disclosed |
| EP-0511948-B1 | Preparation of urethane and carbonate products | MONSANTO CO (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5371183-A | Reacting diamine or polyamine with carbon dioxide in solvent in presence of sterically hindered amidine or guanidine to form salt, reacting with hydrocarbyl dihalide or polyhalide in polar aprotic solvent, polymerizing product | MONSANTO COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5349048-A | Reaction of carbon dioxide with alcohol to form salt in solvent and reacting with hydrocarbyl halide | MONSANTO COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| US-5344934-A | Reaction of carbon dioxide and amine in aprotic solvents | MONSANTO COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5260473-A | Reaction of alcohol and carbon dioxide in aprotic solvent and strong amidine or guanidine base | MONSANTO COMPANY (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0556538-A1 | Blocked tricarbamate compounds | MONSANTO COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| CN-1075475-A | Process for the preparation of carbamate and carbonate products | MONSANTO CO (US) | 1993-08-25 | — | — | CN | disclosed |
| US-5223638-A | Reacting primary or secondary amine with carbon dioxide in presence of strong amidine or guanidine base to form ammonium carbamate salt, reacting in polar aprotic solvent with primary or secondary hydrocarbyl halide | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0511948-A2 | Preparation of urethane and carbonate products | MONSANTO COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | KCNN3, KCNH3, KCNH2 | ATM 2975/4885CTSK 1245/4885CTSS 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.