SCHEMBL1018958

SCHEMBL1018958

C=CCN(CC=C)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.45
CHKA P35790 1/20 0.43
APP P05067 1/20 0.42
OPRM1 P35372 4/20 0.40
OPRD1 P41143 4/20 0.40
OPRK1 P41145 4/20 0.40
ESR2 Q92731 1/20 0.38
PTPN1 P18031 2/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14913062 0.89 ESR1 (0.39) ESR1CHKAAPPOPRM1OPRD1
SCHEMBL851567 0.88 CHKA (0.50) CHKAPTPN1ALDH1A1CYP3A4ALOX15
SCHEMBL10970326 0.83 ESR1 (0.41) ESR1CHKAAPPOPRM1OPRD1
SCHEMBL6692403 0.81 CHKA (0.46) CHKAPTPN1ALDH1A1LMNAMAPT
SCHEMBL6466250 0.81 CHKA (0.46) CHKAPTPN1ALDH1A1MAPTKDM4E
SCHEMBL7162904 0.81 CHKA (0.46) CHKAPTPN1ALDH1A1MAPTKDM4E
SCHEMBL5611650 0.79 ALDH1A1 (0.52) CHKAAPPALDH1A1MEN1CYP3A4
SCHEMBL7854278 0.78 MEN1 (0.47) CHKAPTPN1ALDH1A1LMNAMAPT
SCHEMBL15336561 0.78 APP (0.44) ESR1APPOPRM1OPRD1OPRK1
SCHEMBL971785 0.77 CHKA (0.43) CHKAPTPN1ALDH1A1GAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427572-B1 Process for preparing N-alkylaminophenols and N,N-dialkylaminophenols SUMITOMO CHEMICAL CO (JP) 1994-04-27 EP claimed
EP-0070481-B1 PHOTOGRAPHIC ELEMENTS EMPLOYING NONDIFFUSIBLE PYRIDYLAZO(DIALKYLAMINO)PHENOL MAGENTA DYE-RELEASING COMPOUNDS OR PRECURSORS THEREOF EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-10 EP claimed
US-4434277-A AROMATIC-ALDEHYDE RESINS, MANNICH REACTION ASAHI GLASS COMPANY, LTD. (JP) 1984-02-28 US claimed
JP-5186407-A None JP disclosed
JP-63051364-A None JP disclosed
CN-111480210-B Electrolyte composition and use thereof 株式会社大赛璐 2022-02-25 CN disclosed
CN-109134336-B Diaryl ether compound, preparation method and application thereof 北京大学深圳研究生院 2021-08-03 CN disclosed
EP-3726550-A1 ELECTROLYTE COMPOSITION AND USE THEREOF Daicel Corporation (JP) 2020-10-21 EP disclosed
US-20200294726-A1 ELECTROLYTE COMPOSITION AND USE THEREOF DAICEL CORPORATION (JP) 2020-09-17 US disclosed
EP-3275862-B1 METHOD FOR PRODUCING 1-(4-HYDROXYPHENYL)-4-(4-TRIFLUOROMETHOXYPHENOXY)PIPERIDINE OR SALT THEREOF OTSUKA PHARMA CO LTD (JP) 2020-08-12 EP disclosed
CN-111480210-A Electrolyte composition and use thereof 株式会社大赛璐 2020-07-31 CN disclosed
US-4212822-A Preparation of o-dialkylaminomethylphenols BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
EP-0011091-A1 Process for preparing alkyl- or arylthiomethyl-phenols BAYER AG (DE) 1980-05-28 EP disclosed
US-4195151-A PRODUCTION OF POLYURETHANE ELASTOMERS UNION CARBIDE CORPORATION (US) 1980-03-25 US disclosed
US-4194984-A OIL ADDITIVES, ANTISLUDGING EXXON RESEARCH & ENGINEERING CO. (US) 1980-03-25 US disclosed
US-4187193-A Micro-capsules containing ureido fluoran chromogenic compounds CHAMPION INTERNATIONAL CORPORATION (US) 1980-02-05 US disclosed
US-4156061-A ETHYLENE, AN ALPHA-OLEFIN AND A NON-CONJUGATED DIOLEFIN EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-22 US disclosed
US-4107106-A Phenol-aldehyde-amine resin/glycol curatives for energy absorbing polyurethanes UNION CARBIDE CORPORATION (US) 1978-08-15 US disclosed
US-4104437-A Pressure-sensitive copy system including ureido fluoran chromogenic compounds CHAMPION INTERNATIONAL CORPORATION (US) 1978-08-01 US disclosed
US-4051050-A Oil-soluble anionic-graft polymer of ethylene-propylene copolymer and anionically polymerizable monomer having utility as multifunctional V. I. improver for lubricating oils EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-27 US disclosed