Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851567 | 0.88 | CHKA (0.50) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL6692403 | 0.81 | CHKA (0.46) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL6466250 | 0.81 | CHKA (0.46) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL7162904 | 0.81 | CHKA (0.46) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL5147075 | 0.80 | CHKA (0.42) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL5611650 | 0.79 | ALDH1A1 (0.52) | CHKAGAACRHR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL127344 | 0.77 | ALDH1A1 (0.52) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL1018958 | 0.77 | ESR1 (0.45) | CHKAGAAPTPN1CYP1A2ALDH1A1 | |
| SCHEMBL608140 | 0.77 | ALDH1A1 (0.50) | CHKAGAAPTPN1CNR1CNR2 | |
| SCHEMBL8001371 | 0.77 | PYCR1 (0.50) | CHKAGAAPTPN1CRHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394737-B2 | Preparation of activating supports | TOTAL PETROCHEMICALS RESEARCH FELUY Seneffe (BE) | 2013-03-12 | — | — | US | disclosed |
| US-20110009582-A1 | Preparation of Activating Supports | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-01-13 | — | — | US | disclosed |
| EP-2025403-A1 | Preparation of activating supports | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-02-18 | — | — | EP | disclosed |