Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 18/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054761 | 0.83 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL898526 | 0.83 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL180599 | 0.78 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL180547 | 0.78 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL10188659 | 0.78 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL180810 | 0.77 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL902024 | 0.76 | DGAT1 (0.43) | DGAT1ALDH1A1MAPT | |
| SCHEMBL180643 | 0.76 | DGAT1 (0.57) | DGAT1ALDH1A1 | |
| SCHEMBL15073266 | 0.76 | DGAT1 (0.52) | DGAT1ALDH1A1 | |
| SCHEMBL14971538 | 0.75 | DGAT1 (0.45) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |