Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054761 | 1.00 | DGAT1 (0.54) | DGAT1SOAT1 | |
| SCHEMBL902024 | 0.87 | DGAT1 (0.43) | DGAT1SOAT1 | |
| SCHEMBL180599 | 0.86 | DGAT1 (0.54) | DGAT1SOAT1 | |
| SCHEMBL180547 | 0.86 | DGAT1 (0.54) | DGAT1SOAT1 | |
| SCHEMBL10188659 | 0.85 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL15073266 | 0.84 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL180899 | 0.83 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL10189658 | 0.83 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL14971580 | 0.81 | DGAT1 (0.54) | DGAT1SOAT1 | |
| SCHEMBL14971574 | 0.81 | DGAT1 (0.54) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096093-A1 | COMPOUNDS AS DGAT-1 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |