SCHEMBL10190451

SCHEMBL10190451

Cc1cc(-c2ccc(O)cc2)c(C)cc1-c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.56
ESR1 P03372 9/20 0.52
HSD17B1 P14061 1/20 0.52
ABL1 P00519 2/20 0.48
ABCB1 P08183 2/20 0.48
BCR P11274 2/20 0.48
GAA P10253 1/20 0.48
USP7 Q93009 1/20 0.46
SENP1 Q9P0U3 1/20 0.46
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28204878 0.95 ESR2 (0.52) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL15929640 0.93 ACHE (0.59) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL17625680 0.93 GAA (0.54) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL29929314 0.92 ESR2 (0.54) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL20147811 0.91 ESR2 (0.50) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL3817112 0.89 KDM4E (0.54) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL29738442 0.85 ESR2 (0.76) ESR2ESR1HSD17B1
SCHEMBL439874 0.85 ESR2 (0.76) ESR2ESR1HSD17B1
SCHEMBL1759436 0.84 ESR2 (0.47) ESR2ESR1HSD17B1ABL1ABCB1
SCHEMBL10190449 0.84 MGAM (0.53) ESR2ESR1HSD17B1ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed