Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10190451 | 0.93 | ESR2 (0.56) | ACHEESR2HSD17B1ESR1GAA | |
| SCHEMBL28204878 | 0.88 | ESR2 (0.52) | ESR2HSD17B1ESR1ESRRAGAA | |
| SCHEMBL23908222 | 0.88 | TDP1 (0.47) | ACHEESR2MAOBLDHALDHB | |
| SCHEMBL17625680 | 0.86 | GAA (0.54) | ESR2HSD17B1ESR1GAAABL1 | |
| SCHEMBL29929314 | 0.86 | ESR2 (0.54) | ACHEESR2HSD17B1ESR1ESRRA | |
| SCHEMBL19334620 | 0.86 | ACHE (0.65) | ACHEESR2ESR1MAOBCA12 | |
| SCHEMBL15929638 | 0.86 | MGAM (0.53) | ACHEESR2ESR1GAAABL1 | |
| SCHEMBL13463287 | 0.85 | ESR2 (0.55) | ACHEESR2HSD17B1ESR1MAOB | |
| SCHEMBL14173109 | 0.85 | ESR2 (0.55) | ACHEESR2HSD17B1ESR1MAOB | |
| SCHEMBL20147811 | 0.84 | ESR2 (0.50) | ESR2HSD17B1ESR1ESRRAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035287-B2 | Polymeric materials for use in metal-oxide-semiconductor field-effect transistors | POLYERA CORPORATION (US) | 2015-05-19 | — | — | US | disclosed |
| US-20140217395-A1 | Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors | POLYERA CORPORATION (US) | 2014-08-07 | — | — | US | disclosed |