SCHEMBL10191583

SCHEMBL10191583

CCC1(CC)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)C(OC(C)=O)[C@H]1C

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PRMT6 Q96LA8 1/20 0.53
▸ PRKAB2 O43741 1/20 0.43
▸ PRKAG1 P54619 1/20 0.43
▸ PRKAA2 P54646 1/20 0.43
▸ PRKAA1 Q13131 1/20 0.43
▸ PRKAG3 Q9UGI9 1/20 0.43
▸ PRKAG2 Q9UGJ0 1/20 0.43
▸ PRKAB1 Q9Y478 1/20 0.43
▸ P2RY12 Q9H244 7/20 0.42
▸ BMPR1B O00238 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445611 1.00 PRMT6 (0.53) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL16473389 1.00 PRMT6 (0.53) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL12851609 0.92 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL12851855 0.89 PRMT6 (0.46) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL12851647 0.89 PRMT6 (0.46) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL12386688 0.89 PRMT6 (0.51) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL16473357 0.89 PRMT6 (0.44) PRMT6P2RY12
SCHEMBL16998325 0.88 PRMT6 (0.52) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL10072467 0.87 PRMT6 (0.51) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL16473413 0.87 ADORA2A (0.47) BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120108800-A1 METHOD FOR SYNTHESIZING NUCLEIC ACID TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108800-A1 METHOD FOR SYNTHESIZING NUCLEIC ACID RNGTT, NSUN2, NSUN3 PRMT6 1105/4885PRKAB2 2128/4885PRKAG1 2284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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