SCHEMBL1019182

SCHEMBL1019182

c1coc(C2=Nc3ccccc3C2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.59
CASP1 P29466 3/20 0.59
ALDH1A1 P00352 5/20 0.57
TP53 P04637 1/20 0.57
GAA P10253 2/20 0.52
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
KDM4E B2RXH2 6/20 0.51
RXFP1 Q9HBX9 1/20 0.51
POLB P06746 4/20 0.48
MAPT P10636 4/20 0.44
PKM P14618 3/20 0.44
RECQL P46063 3/20 0.44
HPGD P15428 3/20 0.39
ALOX15 P16050 2/20 0.39
PTPN7 P35236 2/20 0.39
BLM P54132 2/20 0.39
CASP7 P55210 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5021700 0.78 NOS3 (0.46) ALDH1A1GAAMEN1KMT2AKDM4E
SCHEMBL1550046 0.77 NPSR1 (0.50) NPSR1CASP1ALDH1A1TP53GAA
SCHEMBL11887431 0.74 NPSR1 (1.00) NPSR1CASP1ALDH1A1TP53GAA
SCHEMBL13961627 0.72 HRH4 (0.46) NPSR1CASP1ALDH1A1TP53GAA
SCHEMBL10039081 0.72 MAPT (0.49) NPSR1ALDH1A1TP53GAAKMT2A
SCHEMBL2433109 0.71 MAPT (0.53) NPSR1ALDH1A1TP53GAAMEN1
SCHEMBL30136580 0.71 MAPT (0.53) NPSR1ALDH1A1TP53GAAMEN1
SCHEMBL1021869 0.70 DPP4 (0.46) NPSR1ALDH1A1KDM4EMAPTHPGD
SCHEMBL13987099 0.68 NOS3 (0.38) ALDH1A1TP53GAAMEN1KMT2A
SCHEMBL12541807 0.68 NOS3 (0.38) ALDH1A1TP53GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP claimed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP claimed
EP-2271306-A1 DECORATIVE COSMETIC COMPOSITIONS Bayer MaterialScience AG (DE) 2011-01-12 EP disclosed
EP-2271305-A1 SUN PROTECTION COMPOSITIONS Bayer MaterialScience AG (DE) 2011-01-12 EP disclosed
WO-2009118103-A1 SUN PROTECTION COMPOSITIONS BAYER MATERIALSCIENCE AG (DE) 2009-10-01 WO disclosed
WO-2009118106-A1 DECORATIVE COSMETIC COMPOSITIONS BAYER MATERIALSCIENCE AG (DE) 2009-10-01 WO disclosed
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP disclosed
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP disclosed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed