SCHEMBL1021869

SCHEMBL1021869

c1ccc2c(c1)CC(c1cc3ccccc3o1)=N2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.46
MAOB P27338 4/20 0.43
MAOA P21397 3/20 0.43
ALDH1A1 P00352 3/20 0.43
ADRA2A P08913 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
HSD17B10 Q99714 1/20 0.43
NISCH Q9Y2I1 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 3/20 0.42
METAP2 P50579 1/20 0.41
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2426313 0.80 ALDH1A1 (0.51) MAOBALDH1A1KDM4EHPGDHSD17B10
SCHEMBL5021700 0.73 NOS3 (0.46) ALDH1A1KDM4ECYP2D6NPC1RAB9A
SCHEMBL340826 0.71 MAPT (0.38) DPP4MAOBMAOAALDH1A1ADRA2A
SCHEMBL103158 0.71 MAOB (0.63) MAOBMAOAALDH1A1ADRA2AKDM4E
SCHEMBL30036439 0.71 MAOB (0.63) MAOBMAOAALDH1A1ADRA2AKDM4E
SCHEMBL1019182 0.70 NPSR1 (0.59) ALDH1A1KDM4EHPGDHSD17B10NPC1
SCHEMBL14287895 0.69 NQO1 (0.45) ALDH1A1KDM4EHPGDCYP1A2HSD17B10
SCHEMBL10039081 0.68 MAPT (0.49) ALDH1A1KDM4ENPC1RAB9AMAPT
SCHEMBL30561833 0.68 MAOB (0.55) MAOBMAOAALDH1A1ADRA2AKDM4E
SCHEMBL13961627 0.68 HRH4 (0.46) MAOAALDH1A1KDM4ECYP2D6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP claimed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP claimed
EP-4114347-A1 COSMETIC COMPOSITION FOR FORMING A FILM HAVING ELEVATED ELASTICITY AND EXTENSIBILITY Covestro Deutschland AG (DE) 2023-01-11 EP disclosed
EP-3177267-B1 POLYURETHANEUREA SOLUTIONS FOR COSMETIC COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2022-01-05 EP disclosed
EP-3888627-A1 BIO-BASED POLYURETHANE DISPERSIONS FOR DECORATIVE COSMETIC APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 EP disclosed
EP-3889196-A1 BIOBASED POLYURETHANE DISPERSIONS FOR SUNSCREEN APPLICATIONS Covestro Deutschland AG (DE) 2021-10-06 EP disclosed
EP-2271307-B1 SKIN CARE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2019-11-20 EP disclosed
EP-2271305-B1 SUNSCREEN COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2019-09-04 EP disclosed
EP-2271306-B1 DECORATIVE COSMETIC COMPOUNDS COVESTRO DEUTSCHLAND AG (DE) 2019-08-28 EP disclosed
EP-2542212-B1 SUN PROTECTION COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2018-02-21 EP disclosed
EP-2457846-A2 Dispensing module for cosmetic compounds Bayer MaterialScience AG (DE) 2012-05-30 EP disclosed
WO-2012049146-A2 POLYURETHANE-BASED SUNSCREEN COMPOSITION CONTAINING SPECIAL FILTER SUBSTANCES BAYER MATERIALSCIENCE AG (DE) 2012-04-19 WO disclosed
EP-2271307-A2 SKIN CARE COMPOSITION Bayer MaterialScience AG (DE) 2011-01-12 EP disclosed
EP-2106833-A1 Particle derived from drying a liquid nano-uric dispersion Bayer MaterialScience AG (DE) 2009-10-07 EP disclosed
WO-2009118107-A2 SKIN CARE COMPOSITION BAYER MATERIALSCIENCE AG (DE) 2009-10-01 WO disclosed
EP-2105126-A1 Decorative cosmetic compounds Bayer MaterialScience AG (DE) 2009-09-30 EP disclosed
EP-2105125-A1 Skin care composition Bayer MaterialScience AG (DE) 2009-09-30 EP disclosed
EP-2105124-A1 Sunscreen compositions Bayer MaterialScience AG (DE) 2009-09-30 EP disclosed
EP-0010063-B1 PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES CIBA-GEIGY AG (CH) 1982-12-29 EP disclosed
EP-0010063-A2 Process for the preparation of furanyl-benzazoles CIBA-GEIGY AG (CH) 1980-04-16 EP disclosed