SCHEMBL1019195

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019840	0.88	EGFR (0.39)	HSP90AA1MAPTMEN1KMT2ATSHR
	SCHEMBL1019040	0.88	P2RX3 (0.41)	MAPTNPSR1TSHRHSD17B10P2RX3
	SCHEMBL31425472	0.88	P2RX3 (0.41)	MAPTNPSR1TSHRHSD17B10P2RX3
	SCHEMBL1018764	0.87	HSP90AA1 (0.44)	HSP90AA1MAPTTSHREGFRBACE1
	SCHEMBL1021339	0.83	KDM4E (0.49)	HSP90AA1MAPTMEN1KMT2ANPSR1
	SCHEMBL1019801	0.80	TSHR (0.51)	HSP90AA1THRATHRBMAPTMEN1
	SCHEMBL1022138	0.78	HSP90AA1 (0.42)	HSP90AA1MEN1KMT2ATSHREGFR
	SCHEMBL22789779	0.78	HMGCR (0.46)	MAPTTSHRHSD17B10EGFRCLCN2
	SCHEMBL14930787	0.76	CYP3A4 (0.51)	TSHREGFRBACE1
	SCHEMBL1018574	0.75	CHEK1 (0.41)	HSP90AA1MAPTTSHREGFRBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.