Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10193226 | 0.88 | BACE1 (0.58) | BACE1 | |
| SCHEMBL10193015 | 0.86 | BACE1 (0.59) | BACE1 | |
| SCHEMBL10193693 | 0.86 | BACE1 (0.61) | BACE1 | |
| SCHEMBL10193676 | 0.83 | BACE1 (0.47) | BACE1APP | |
| SCHEMBL10193575 | 0.82 | BACE1 (0.51) | BACE1 | |
| SCHEMBL10194912 | 0.78 | PRSS1 (0.46) | BACE1 | |
| SCHEMBL10194085 | 0.76 | ACKR3 (0.50) | BACE1 | |
| SCHEMBL10193709 | 0.75 | SMN1; SMN2 (0.42) | BACE1 | |
| SCHEMBL10194093 | 0.74 | BACE1 (0.42) | BACE1 | |
| SCHEMBL10194162 | 0.74 | BACE1 (0.45) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415756-A1 | ISOTHIOUREA DERIVATIVES OR ISOUREA DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | Shionogi&Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |