SCHEMBL824622

SCHEMBL824622

[C-]#[N+]c1c(C)nn(-c2ccccc2)c1/N=N/c1c(C)nn(-c2ncccn2)c1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.53
SMN1; SMN2 Q16637 12/20 0.53
RAB9A P51151 11/20 0.53
NPC1 O15118 10/20 0.53
TDP1 Q9NUW8 5/20 0.53
HPGD P15428 5/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPK1 P28482 7/20 0.48
KMT2A Q03164 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MEN1 O00255 2/20 0.48
HTT P42858 2/20 0.48
ALOX12 P18054 1/20 0.48
LMNA P02545 5/20 0.47
NFKB1 P19838 3/20 0.40
NFKB2 Q00653 3/20 0.40
RELA Q04206 3/20 0.40
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824624 0.89 MAPT (0.55) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824866 0.85 SMN1; SMN2 (0.64) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824562 0.84 MAPT (0.59) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824588 0.82 MAPT (0.35) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824589 0.81 MAPT (0.34) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824868 0.81 MAPT (0.34) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL10194298 0.80 MAPT (0.46) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL10194372 0.77 MAPT (0.43) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824849 0.76 MAPT (0.60) MAPTSMN1; SMN2RAB9ANPC1TDP1
SCHEMBL824558 0.76 MAPT (0.39) MAPTSMN1; SMN2RAB9ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142519-B2 Azo pigment, and pigment dispersion, coloring composition and ink composition for inkjet recording containing the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258036-A1 AZO PIGMENT, AND PIGMENT DISPERSION, COLORING COMPOSITION AND INK COMPOSITION FOR INKJET RECORDING CONTAINING THE SAME WNT1, CYP1A1, CYP1B1 MAPT 372/4885SMN1; SMN2 3717/4885RAB9A 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.