Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 11/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194915 | 0.92 | ESRRA (0.52) | ESRRAFAAHMGLLSIGMAR1HTR7 | |
| SCHEMBL10196715 | 0.86 | ESRRA (0.53) | ESRRAFAAHMGLLSIGMAR1 | |
| SCHEMBL10194711 | 0.78 | ESRRA (0.60) | ESRRAFAAHMGLL | |
| SCHEMBL10195783 | 0.78 | ESRRA (0.55) | ESRRAFAAHMGLL | |
| SCHEMBL10195750 | 0.76 | ESRRA (0.62) | ESRRAFAAHMGLL | |
| SCHEMBL10196894 | 0.75 | ESRRA (0.56) | ESRRAFAAHMGLLPOLB | |
| SCHEMBL10194732 | 0.73 | ESRRA (0.44) | ESRRA | |
| SCHEMBL10195780 | 0.73 | ESRRA (0.44) | ESRRA | |
| SCHEMBL17850412 | 0.71 | ESRRA (0.48) | ESRRA | |
| SCHEMBL10194692 | 0.70 | SIGMAR1 (0.44) | FAAHMGLLSIGMAR1POLBHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084704-A1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO S.A. (CH) | 2012-06-28 | — | — | WO | disclosed |