SCHEMBL1019564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1148717	0.95	GLRA1 (0.49)	HPGDALDH1A1HTTSMPD1HDAC1
	SCHEMBL1018517	0.89	GLRA1 (0.44)	HPGDALDH1A1HTTSMPD1HDAC1
	SCHEMBL22354782	0.89	SMN1; SMN2 (0.49)	HPGDALDH1A1HTTSMPD1HDAC1
	SCHEMBL1018714	0.88	LMNA (0.53)	HPGDSMPD1HDAC1HDAC8HDAC6
	SCHEMBL4566987	0.85	GLRA1 (0.47)	HPGDALDH1A1HTTSMPD1HDAC1
	SCHEMBL31363066	0.85	GLRA1 (0.49)	ALDH1A1HTTPOLBGLRA1LMNA
	SCHEMBL383740	0.83	FOLH1 (0.55)	ALDH1A1CTSVCTSLPOLBGLRA1
	SCHEMBL16097521	0.82	SMPD1 (0.50)	HPGDALDH1A1HTTSMPD1HDAC1
	SCHEMBL1764051	0.82	ABCB1 (0.59)	HPGDSMPD1HDAC1HDAC8HDAC6
	SCHEMBL19569167	0.82	TSHR (0.49)	HPGDALDH1A1HTTSMPD1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.