SCHEMBL10195692

SCHEMBL10195692

N#Cc1c(SCc2csc(-c3ccc(Cl)cc3)n2)nc2[nH]ncc2c1-c1ccc(CCCO)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 19/20 0.56
SLC6A3 Q01959 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382961 0.88 ADORA1 (0.73) ADORA1SLC6A3
SCHEMBL7900477 0.85 ADORA1 (0.66) ADORA1SLC6A3
SCHEMBL7900475 0.84 ADORA1 (0.78) ADORA1SLC6A3
SCHEMBL15501124 0.82 ADORA1 (0.77) ADORA1SLC6A3
SCHEMBL7893973 0.80 ADORA1 (0.59) ADORA1SLC6A3
SCHEMBL7898774 0.80 ADORA1 (0.57) ADORA1SLC6A3
SCHEMBL8003455 0.79 ADORA1 (0.53) ADORA1SLC6A3
SCHEMBL8011126 0.79 ADORA1 (0.56) ADORA1SLC6A3
SCHEMBL8008750 0.79 ADORA1 (0.65) ADORA1SLC6A3
SCHEMBL10194189 0.77 ADORA1 (0.53) ADORA1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2235011-B1 SUBSTITUTED PYRROLO[2, 3-B]AND PYRAZOLO[3, 4-B]PYRIDINES FOR USE AS ADENOSINE RECEPTOR LIGANDS Bayer Pharma AG (DE) 2012-01-25 EP disclosed