Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DUT | P33316 | 11/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057367 | 0.81 | DUT (0.43) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL16503452 | 0.81 | DUT (0.39) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL16576318 | 0.79 | PKM (0.40) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL14391833 | 0.77 | PKM (0.41) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL19171430 | 0.77 | PKM (0.52) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL20599908 | 0.74 | PKM (0.57) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL14544299 | 0.74 | GRIA1 (0.48) | — | |
| SCHEMBL14391634 | 0.74 | PKM (0.50) | PKMALDH1A1LMNADUTENPP1 | |
| SCHEMBL11954659 | 0.74 | GRIA1 (0.48) | — | |
| SCHEMBL12748529 | 0.74 | TYMP (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012125900-A1 | 2'-ALLENE-SUBSTITUTED NUCLEOSIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2012-09-20 | — | — | WO | disclosed |