Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181578 | 0.72 | ALDH1A1 (0.37) | POLBKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11620624 | 0.68 | KDM4E (0.41) | POLBKDM4ERAB9AALDH1A1GAA | |
| SCHEMBL82402 | 0.67 | HRH3 (0.70) | POLBALDH1A1LMNANPC1 | |
| SCHEMBL12765222 | 0.65 | SIGMAR1 (0.70) | POLBSMN1; SMN2KMT2ARECQL | |
| SCHEMBL25092918 | 0.64 | HRH3 (0.64) | POLBRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL82383 | 0.64 | ALDH1A1 (0.67) | KDM4ERAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11529719 | 0.64 | POLB (0.78) | POLBKDM4ERAB9ASMN1; SMN2LMNA | |
| SCHEMBL13841388 | 0.64 | TSHR (0.60) | POLBKDM4ERAB9AGAAHSD17B10 | |
| SCHEMBL11864 | 0.63 | HRH3 (0.71) | POLBALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL13103802 | 0.63 | POLB (0.48) | POLBALDH1A1SMN1; SMN2RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084704-A1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO S.A. (CH) | 2012-06-28 | — | — | WO | disclosed |