Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 16/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | CHRNB4 | P30926 | 10/20 | 0.97 |
| ▸ | CHRNA3 | P32297 | 10/20 | 0.97 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.97 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.97 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.97 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.97 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.97 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stilonium SCHEMBL26104 | 0.98 | CHRNA7 (1.00) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| Stilonium SCHEMBL26105 | 0.98 | CHRNA7 (1.00) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL13385235 | 0.84 | CHRNA7 (1.00) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL11423649 | 0.83 | CHRNA7 (0.96) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL5741015 | 0.81 | RELA (0.72) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL1618632 | 0.81 | RELA (0.72) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL80814 | 0.77 | CHRNA7 (0.72) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL436231 | 0.77 | RELA (1.00) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL5496245 | 0.77 | RELA (1.00) | CHRNA7CYP1A2MAPTKDM4EMEN1 | |
| SCHEMBL5739190 | 0.77 | CHRNA7 (0.68) | CHRNA7CYP1A2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218748-A2 | BMP-MIMETICS | Christian-Albrechts-Universität zu Kiel (DE) | 2023-08-02 | — | — | EP | disclosed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| WO-2019042889-A1 | BMP-MIMETICS | TECHNISCHE UNIVERSITÄT DORTMUND (DE) | 2019-03-07 | — | — | WO | disclosed |
| US-20140234271-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-08-21 | — | — | US | disclosed |
| US-8748177-B2 | Compositions for proliferation of cells and related methods | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-06-10 | — | — | US | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |
| US-20110301105-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2011-12-08 | — | — | US | disclosed |
| WO-2010039679-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234271-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | MKI67, KRT18, PROX1 | CHRNA7 4048/4885CYP1A2 3168/4885MAPT 2714/4885 |
| US-20110301105-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | MKI67, KRT18, PROX1 | CHRNA7 4048/4885CYP1A2 3168/4885MAPT 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.