Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766314 | 0.91 | KMT2A (0.55) | KMT2AMEN1NPSR1GAATSHR | |
| SCHEMBL9610938 | 0.89 | KMT2A (0.74) | KMT2AMEN1NPSR1GAATSHR | |
| SCHEMBL17843850 | 0.86 | SMN1; SMN2 (0.68) | KMT2AMEN1NPSR1GAATSHR | |
| SCHEMBL7895100 | 0.84 | PTPN1 (0.68) | KMT2AMEN1NPSR1GAATSHR | |
| SCHEMBL26553770 | 0.84 | SPHK1 (0.65) | KMT2AMEN1LMNASMN1; SMN2RAB9A | |
| SCHEMBL13144615 | 0.83 | ALDH1A1 (0.58) | KMT2AMEN1NPSR1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25403004 | 0.83 | SPHK1 (0.64) | KMT2AMEN1LMNASMN1; SMN2RAB9A | |
| SCHEMBL6956537 | 0.82 | RAB9A (0.82) | KMT2AMEN1GAATSHRLMNA | |
| SCHEMBL17845335 | 0.82 | MEN1 (0.61) | KMT2AMEN1NPSR1GAATSHR | |
| SCHEMBL13746002 | 0.82 | ALDH1A1 (0.72) | KMT2AMEN1TSHRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006104-A2 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | Academia Sinica, Taiwan (TW) | 2012-01-12 | — | — | WO | disclosed |