SCHEMBL1019849

SCHEMBL1019849

C=C(C)C(=O)OC(CC)[SiH2]O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27415907 0.82 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL4512356 0.81 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL1014718 0.81 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL21378212 0.80
SCHEMBL9644599 0.79 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL28330737 0.79 TSHR (0.41) TSHRALDH1A1THRB
Hydrogen Sulfide SCHEMBL21253275 0.79 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL9860071 0.79 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL29087990 0.79 TSHR (0.36) TSHRALDH1A1THRB
Hydrogen Sulfide SCHEMBL23421906 0.78 THRB (0.37) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020007822-A1 BISMUTH METALLIC (0) NANOPARTICLES, PROCESS OF MANUFACTURING AND USES THEREOF CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM) (FR) 2020-01-09 WO claimed
CN-108314896-A A kind of high bonding easily stores one-component add-on type liquid silicon rubber 湖南利德电子浆料股份有限公司 2018-07-24 CN claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
EP-1838765-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES Michelin Recherche et Technique S.A. (CH) 2007-10-03 EP claimed
WO-2006069792-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO claimed
WO-2020007822-A1 BISMUTH METALLIC (0) NANOPARTICLES, PROCESS OF MANUFACTURING AND USES THEREOF CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM) (FR) 2020-01-09 WO disclosed
CN-108314896-A A kind of high bonding easily stores one-component add-on type liquid silicon rubber 湖南利德电子浆料股份有限公司 2018-07-24 CN disclosed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US disclosed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US disclosed
EP-0306700-B1 Coating composition and wheel coated with the same for vehicles OSAKA YUKI KAGAKU KOGYO (JP) 1993-10-27 EP disclosed
EP-0184924-A2 Lens composition, articles and method of manufacture PARAGON OPTICAL INC (US) 1986-06-18 EP disclosed