SCHEMBL10198970

SCHEMBL10198970

CC(=O)NC1C(O)CC(C(=O)O)(C(C)(C)C)OC1C(O)C(O)CO

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 3/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ SELL P14151 1/20 0.45
▸ SELP P16109 1/20 0.45
▸ NEU2 Q9Y3R4 3/20 0.45
▸ NEU4 Q8WWR8 2/20 0.45
▸ NEU3 Q9UQ49 2/20 0.45
▸ NEU1 Q99519 1/20 0.45
▸ MAG P20916 2/20 0.41
▸ SIGLEC7 Q9Y286 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15144450 0.91 NANP (0.52) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL21049933 0.84 NANP (0.71) NANPL3MBTL1SELLSELPNEU2
SCHEMBL23591351 0.83 L3MBTL1 (0.49) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL22943658 0.82 NANP (0.72) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL22879166 0.82 NANP (0.72) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL21067569 0.82 NANP (0.72) NANPL3MBTL1SELLSELPNEU2
SCHEMBL23640238 0.82 NANP (0.54) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL24274184 0.82 NANP (0.72) NANPL3MBTL1SELLSELPNEU2
SCHEMBL23635227 0.82 NANP (0.54) NANPL3MBTL1SELLSELPNEU2
Sialic Acid SCHEMBL23366253 0.82 NANP (0.72) NANPL3MBTL1SELLSELPNEU2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200056222-A1 Flash and Glow 1,2-Dioxetanes Life Technologies Corporation 2020-02-20 — — US disclosed
US-20170321245-A1 Flash and Glow 1,2-Dioxetanes Life Technologies Corporation 2017-11-09 — — US disclosed
WO-2012151142-A2 FLASH AND GLOW 1,2-DIOXETANES Life Technologies Corporation (US) 2012-11-08 — — WO disclosed
WO-2012006351-A1 IN SITU CHEMILUMINESCENT SUBSTRATES AND ASSAYS Life Technologies Corporation (US) 2012-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170321245-A1 Flash and Glow 1,2-Dioxetanes GLO1, DDX41, GDA NANP 1918/4885L3MBTL1 3591/4885SELL 1093/4885
US-20200056222-A1 Flash and Glow 1,2-Dioxetanes GLO1, DDX41, GDA NANP 1918/4885L3MBTL1 3591/4885SELL 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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